During a Major Earthquake
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Seek shelter under a desk or table if you can. 
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If no shelter is available, move away from potentially harmful things (breaking glass, chemicals), make yourself as small as possible and cover your head. 
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Remain in this sheltered position until the shaking stops. 
Actions Immediately After a Major Earthquake
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Assess your situation. Take direction from law enforcement when possible. 
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Be prepared to seek shelter again. Aftershocks can be more or less powerful than the original earthquake. 
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Decide if evacuation from the building is the proper course of action. 
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If you work in a lab, take these important steps to take before leaving if it is safe to do so. - Turn off gas burners.
- Check quickly for fires, fire hazards, or spilled chemicals.
- Check for injured or physically limited people who might have trouble evacuating the building. Help those only to your ability.
- Close the lab door as you leave.
- Report crucial items, hazards, or location of injured persons to the appropriate official at the emergency assembly area.
 
The USGS has a great website regarding earthquakes and what to do.
 
 